Dichloromethane → tert-Butyl 4-(4-(trifluoromethoxy)benzoyl)piperidine-1-carboxylate

HRID 95429Notes

Reaction equation

HRID 95429 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH:14]([c:15]2[cH:16][cH:17][c:18]([O:21][C:22]([F:23])([F:24])[F:25])[cH:19][cH:20]2)[OH:26])[CH2:12][CH2:13]1.[Cl:38][CH2:39][Cl:40].[O:27]=[Cr:28]([Cl:29])([O-:30])=[O:31].[nH+:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([C:14]([c:15]2[cH:16][cH:17][c:18]([O:21][C:22]([F:23])([F:24])[F:25])[cH:19][cH:20]2)=[O:26])[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 4989215PyridiniumHCID 120527841-Boc-4-[Hydroxy-(4-trifluoromethoxyphenyl)methyl]piperidineHCID 178418299HCID 178418299, compound

Product 1

HCID 68968884tert-Butyl 4-(4-(trifluoromethoxy)benzoyl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-8c8518d2f2364f7bba2c220751c05a1e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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