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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 954396Generated: October 26, 2026

Methanol → 5-(3-Fluoro-phenyl)-3-[isopropyl-(4-methyl-cyclohexanecarbonyl)-amino]-thiophene-2-carboxylic acid methyl ester

https://huagongshe.com/reaction/954396

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantSodium ionHCID 923—
ReactantTolueneHCID 1140—
ReactantCarbonate IonHCID 19660—
Reactant3-Fluorophenylboronic acidHCID 2733986—
Reactant5-Bromo-3-[isopropyl-(4-methyl-cyclohexanecarbonyl)-amino]-thiophene-2-carboxylic acid methyl esterHCID 20775768—
ReactantHCID 178420554HCID 178420554—
Product5-(3-Fluoro-phenyl)-3-[isopropyl-(4-methyl-cyclohexanecarbonyl)-amino]-thiophene-2-carboxylic acid methyl esterHCID 59752316—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-adb462ccd0e34e2fbac1c1f45c10baf0
Source noteValidation data from https://doi.org/10.1039/C8SC04228D