Ethanol → 6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline

HRID 954591Notes

Reaction equation

HRID 954591 reaction equation
[CH3:29][CH2:30][OH:31].[Cl:5][CH2:6][C:7](=[O:8])[N:9]1[CH:10]([c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[c:11]2[cH:12][c:13]([O:21][CH3:22])[c:14]([O:19][CH3:20])[cH:15][c:16]2[CH2:17][CH2:18]1.[NH2:1][C:2](=[S:3])[NH2:4]>>[NH:9]1[CH:10]([c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[c:11]2[cH:12][c:13]([O:21][CH3:22])[c:14]([O:19][CH3:20])[cH:15][c:16]2[CH2:17][CH2:18]1

Participants

4

Reactant 3

HCID 702EthanolHCID 2723790ThioureaHCID 37891952-Chloro-1-(6,7-dimethoxy-1-phenyl-3,4-dihydro-1H-isoquinolin-2-yl)-ethanone

Product 1

HCID 1511866,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline

Sources & evidence

ORD record
ord-c64fe0b951414923a391bea338e58117
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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