N-[1-[[6-amino-1-oxo-1-(4-pyridin-4-ylpiperazin-1-yl)hexan-2-yl]amino]-3-(7-methyl-1H-indazol-5-yl)-1-oxopropan-2-yl]-4-(2-oxo-1H-quinolin-3-yl)piperidine-1-carboxamide → N-[1-[[6-amino-1-oxo-1-(4-pyridin-4-ylpiperazin-1-yl)hexan-2-yl]amino]-3-(7-methyl-1H-indazol-5-yl)-1-oxopropan-2-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide
Reaction equation
[CH3:1][c:2]1[cH:3][c:4]([CH2:11][CH:12]([C:13](=[O:14])[NH:15][CH:16]([CH2:17][CH2:18][CH2:19][CH2:20][NH:21][C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[C:29]([N:30]2[CH2:31][CH2:32][N:33]([c:36]3[cH:37][cH:38][n:39][cH:40][cH:41]3)[CH2:34][CH2:35]2)=[O:42])[NH:43][C:44](=[O:45])[N:46]2[CH2:47][CH2:48][CH:49]([N:52]3[C:53](=[O:62])[NH:54][c:55]4[cH:56][cH:57][cH:58][cH:59][c:60]4[CH2:61]3)[CH2:50][CH2:51]2)[cH:5][c:6]2[cH:7][n:8][nH:9][c:10]12.[NH2:63][CH2:64][CH2:65][CH2:66][CH2:67][CH:68]([NH:69][C:70](=[O:71])[CH:72]([NH:73][C:74]([N:75]1[CH2:76][CH2:77][CH:78]([c:79]2[c:80](=[O:81])[nH:82][c:83]3[c:84]([cH:85]2)[cH:86][cH:87][cH:88][cH:89]3)[CH2:90][CH2:91]1)=[O:92])[CH2:93][c:94]1[cH:95][c:96]2[c:97]([c:98]([CH3:99])[cH:100]1)[nH:101][n:102][cH:103]2)[C:104](=[O:105])[N:106]1[CH2:107][CH2:108][N:109]([c:110]2[cH:111][cH:112][n:113][cH:114][cH:115]2)[CH2:116][CH2:117]1>>[CH3:1][c:2]1[cH:3][c:4]([CH2:11][CH:12]([C:13](=[O:14])[NH:15][CH:16]([CH2:17][CH2:18][CH2:19][CH2:20][NH2:21])[C:29]([N:30]2[CH2:31][CH2:32][N:33]([c:36]3[cH:37][cH:38][n:39][cH:40][cH:41]3)[CH2:34][CH2:35]2)=[O:42])[NH:43][C:44](=[O:45])[N:46]2[CH2:47][CH2:48][CH:49]([N:52]3[C:53](=[O:62])[NH:54][c:55]4[cH:56][cH:57][cH:58][cH:59][c:60]4[CH2:61]3)[CH2:50][CH2:51]2)[cH:5][c:6]2[cH:7][n:8][nH:9][c:10]12Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-2a5edbcc7dee44cb947980a3c298444c
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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