Ammonia → 6-[4-[1-[6-(2-Hydroxy-2-methylpropyl)-2-oxo-6-phenyl-1,3-oxazinan-3-yl]ethyl]phenyl]pyridine-2-carboxamide
Reaction equation
[NH3:36].[OH:1][C:2]([CH2:3][C:4]1([c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[CH2:5][CH2:6][N:7]([CH:11]([CH3:12])[c:13]2[cH:14][cH:15][c:16](-[c:19]3[cH:20][cH:21][cH:22][c:23]([C:25](=[O:26])[OH:27])[n:24]3)[cH:17][cH:18]2)[C:8](=[O:10])[O:9]1)([CH3:34])[CH3:35]>>[OH:1][C:2]([CH2:3][C:4]1([c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[CH2:5][CH2:6][N:7]([CH:11]([CH3:12])[c:13]2[cH:14][cH:15][c:16](-[c:19]3[cH:20][cH:21][cH:22][c:23]([C:25](=[O:26])[NH2:36])[n:24]3)[cH:17][cH:18]2)[C:8](=[O:10])[O:9]1)([CH3:34])[CH3:35]Participants
3
Sources & evidence
- ORD record
- ord-c207805d88294a43a3141ba5e787a4d0
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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