1-(Bromomethyl)-4-(trifluoromethyl)benzene → 2-(1-(2-(4-chlorophenylamino)-2-oxoethyl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)-4-methyl-N-(pyridin-3-ylmethyl)thiazole-5-carboxamide
Reaction equation
[Br:13][CH2:14][C:15](=[O:16])[NH:17][c:18]1[cH:19][cH:20][c:21]([Cl:24])[cH:22][cH:23]1.[CH3:25][c:26]1[n:27][c:28](-[n:41]2[cH:42][n:43][nH:44][c:45]2=[O:46])[s:29][c:30]1[C:31](=[O:32])[NH:33][CH2:34][c:35]1[cH:36][n:37][cH:38][cH:39][cH:40]1.[F:1][C:2]([F:3])([F:4])[c:5]1[cH:6][cH:7][c:8]([CH2:9][Br:10])[cH:11][cH:12]1>>[CH2:14]([C:15](=[O:16])[NH:17][c:18]1[cH:19][cH:20][c:21]([Cl:24])[cH:22][cH:23]1)[n:44]1[n:43][cH:42][n:41](-[c:28]2[n:27][c:26]([CH3:25])[c:30]([C:31](=[O:32])[NH:33][CH2:34][c:35]3[cH:36][n:37][cH:38][cH:39][cH:40]3)[s:29]2)[c:45]1=[O:46]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-134a8feb5a494c5a820fbc9c71a61c9d
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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