Methanol → 2-Difluoromethyl-5-hydroxy-pyran-4-one
Reaction equation
[B:19]([Br:20])([Br:21])[Br:22].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10](=[O:18])[cH:11][c:12]([CH:15]([F:16])[F:17])[o:13][cH:14]1.[CH3:23][OH:24].[Cl:25][CH2:26][Cl:27]>>[OH:8][c:9]1[c:10](=[O:18])[cH:11][c:12]([CH:15]([F:16])[F:17])[o:13][cH:14]1Participants
5
Sources & evidence
- ORD record
- ord-235406b004874c239d22ca3eb6128613
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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