Potassium Cation → Benzyl-[1-(4-ethynylphenyl)-cyclopropyl]-methylamine

HRID 954783Notes

Reaction equation

HRID 954783 reaction equation
[C:25](=[O:26])([O-:27])[O-:28].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]([CH3:9])[C:10]1([c:13]2[cH:14][cH:15][c:16]([C:19]#[C:20][Si:21]([CH3:22])([CH3:23])[CH3:24])[cH:17][cH:18]2)[CH2:11][CH2:12]1.[CH3:31][OH:32].[K+:29].[K+:30]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]([CH3:9])[C:10]1([c:13]2[cH:14][cH:15][c:16]([C:19]#[CH:20])[cH:17][cH:18]2)[CH2:11][CH2:12]1

Participants

5

Reactant 4

HCID 813Potassium Cation2×HCID 887MethanolHCID 19660Carbonate IonHCID 69548036Benzyl-[-(4-trimethylsilanylethynyl-phenyl)-cyclopropyl]-methylamine

Product 1

HCID 22568949Benzyl-[1-(4-ethynylphenyl)-cyclopropyl]-methylamine

Sources & evidence

ORD record
ord-c4f20bdd27c64b3199f9741969971a69
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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