Methyl chloroformate → Methyl 3-[[5-(2-chloro-4-methoxyphenyl)-3,6-diethylpyrazin-2-yl]amino]-4-ethoxypyrrolidine-1-carboxylate
Reaction equation
[C:1]([N:2]1[CH2:3][CH:4]([O:5][CH2:6][CH3:7])[CH:8]([NH:9][c:10]2[c:11]([CH2:12][CH3:13])[n:14][c:15](-[c:16]3[cH:17][cH:18][c:19]([Cl:20])[cH:21][c:22]3[Cl:23])[c:24]([CH2:25][CH3:26])[n:27]2)[CH2:28]1)(=[O:29])[CH3:30].[Cl:31][c:32]1[c:33](-[c:40]2[n:41][c:42]([CH2:57][CH3:58])[c:43]([NH:48][CH:49]3[CH2:50][NH:51][CH2:52][CH:53]3[O:54][CH2:55][CH3:56])[n:44][c:45]2[CH2:46][CH3:47])[cH:34][cH:35][c:36]([O:38][CH3:39])[cH:37]1.[Cl:59][C:60](=[O:61])[O:62][CH3:63]>>[Cl:31][c:32]1[c:33](-[c:40]2[n:41][c:42]([CH2:57][CH3:58])[c:43]([NH:48][CH:49]3[CH2:50][N:51]([C:60](=[O:61])[O:62][CH3:63])[CH2:52][CH:53]3[O:54][CH2:55][CH3:56])[n:44][c:45]2[CH2:46][CH3:47])[cH:34][cH:35][c:36]([O:38][CH3:39])[cH:37]1Participants
4
Sources & evidence
- ORD record
- ord-6ca735fe08704d3bb036460a5d877fe9
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…