2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → HCID 59526168, compound
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]([CH2:8][c:9]2[n:10][n:11][n:12]([CH2:14][CH2:15][OH:16])[n:13]2)[n:7]1.[NH2:17][c:18]1[s:19][c:20](-[c:26]2[c:27]([F:37])[cH:28][c:29]([C:33]([CH3:34])([CH3:35])[OH:36])[cH:30][c:31]2[F:32])[cH:21][c:22]1[C:23](=[O:24])[NH2:25]>>[c:2]1([NH:17][c:18]2[s:19][c:20](-[c:26]3[c:27]([F:37])[cH:28][c:29]([C:33]([CH3:34])([CH3:35])[OH:36])[cH:30][c:31]3[F:32])[cH:21][c:22]2[C:23](=[O:24])[NH2:25])[cH:3][cH:4][cH:5][c:6]([CH2:8][c:9]2[n:10][n:11][n:12]([CH2:14][CH2:15][OH:16])[n:13]2)[n:7]1Participants
3
Sources & evidence
- ORD record
- ord-5e6d83c784594cb9aef8edbe578455f3
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…