Thionyl Chloride → 8-Chloro-3-(chloromethyl)-2-(2-chlorophenyl)quinoline

HRID 954857Notes

Reaction equation

HRID 954857 reaction equation
[Cl:1][c:2]1[c:3](-[c:8]2[n:9][c:10]3[c:11]([Cl:20])[cH:12][cH:13][cH:14][c:15]3[cH:16][c:17]2[CH2:18][OH:19])[cH:4][cH:5][cH:6][cH:7]1.[S:21]([Cl:22])([Cl:23])=[O:24]>>[Cl:1][c:2]1[c:3](-[c:8]2[n:9][c:10]3[c:11]([Cl:20])[cH:12][cH:13][cH:14][c:15]3[cH:16][c:17]2[CH2:18][Cl:23])[cH:4][cH:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 57707777(2-(2-Chlorophenyl)-8-chloroquinolin-3-yl)methanol

Product 1

HCID 592646338-Chloro-3-(chloromethyl)-2-(2-chlorophenyl)quinoline

Sources & evidence

ORD record
ord-5aec4910242646869dc1d3829ca8b47d
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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