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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 954948Generated: October 25, 2026

2-Fluorobenzoic acid → N-[2-[4-[[3-butyl-5-oxo-1-[5-(propanoylamino)-2-(trifluoromethyl)phenyl]-1,2,4-triazol-4-yl]methyl]-3-fluorophenyl]phenyl]sulfonyl-2-fluorobenzamide

https://huagongshe.com/reaction/954948

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluorobenzoic acidHCID 9935—
Reactant4-(Dimethylamino)pyridineHCID 14284—
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
Reactant1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
Reactant5-n-butyl-2,4-dihydro-4-[(3-fluoro-2'-sulfamoyl-biphenyl-4-yl)methyl]-2-[5-(propionylamino)-2-(trifluoromethyl)phenyl]-3H-1,2,4-triazol-3-oneHCID 9986353—
ProductN-[2-[4-[[3-butyl-5-oxo-1-[5-(propanoylamino)-2-(trifluoromethyl)phenyl]-1,2,4-triazol-4-yl]methyl]-3-fluorophenyl]phenyl]sulfonyl-2-fluorobenzamideHCID 10259447—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-8359caf1139b4cd2878911e8d2d08369
Source noteValidation data from https://doi.org/10.1039/C8SC04228D