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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 954967Generated: October 25, 2026

Dimethylformamide → {2-Chloro-4-[3-(3-methoxy-prop-1-ynyl)-5-(3-morpholin-4-yl-propoxy)phenylsulfanyl]-phenoxy}-acetic Acid Ethyl Ester

https://huagongshe.com/reaction/954967

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
Reactant3-MethoxypropyneHCID 69393—
ReactantCopper iodideHCID 83717—
Reactant{4-[3-Bromo-5-(3-morpholin-4-yl-propoxy)-phenylsulfanyl]-2-chloro-phenoxy}-acetic Acid Ethyl EsterHCID 57791920—
Product{2-Chloro-4-[3-(3-methoxy-prop-1-ynyl)-5-(3-morpholin-4-yl-propoxy)phenylsulfanyl]-phenoxy}-acetic Acid Ethyl EsterHCID 67171218—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-007bc76ea3cd4a2582f9b8b28ca8660e
Source noteValidation data from https://doi.org/10.1039/C8SC04228D