4-Chloro-6-isopropylthieno(2,3-d)pyrimidine → N-(1-(3,5-difluorobenzyl)piperidin-4-yl)-6-isopropylthieno[2,3-d]pyrimidin-4-amine
Reaction equation
[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[s:8][c:9]([CH:11]([CH3:12])[CH3:13])[cH:10]2.[F:14][c:15]1[cH:16][c:17]([CH2:18][N:19]2[CH2:20][CH2:21][CH:22]([NH2:25])[CH2:23][CH2:24]2)[cH:26][c:27]([F:29])[cH:28]1>>[c:2]1([NH:25][CH:22]2[CH2:21][CH2:20][N:19]([CH2:18][c:17]3[cH:16][c:15]([F:14])[cH:28][c:27]([F:29])[cH:26]3)[CH2:24][CH2:23]2)[c:3]2[c:4]([n:5][cH:6][n:7]1)[s:8][c:9]([CH:11]([CH3:12])[CH3:13])[cH:10]2Participants
3
Sources & evidence
- ORD record
- ord-bc7fa2f62de141f6bdc98df505ad0cd3
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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