Acetic Acid → 1-Propanone, 1-[4-(3-azetidinyl)-1-piperazinyl]-

HRID 955040Notes

Reaction equation

HRID 955040 reaction equation
[CH3:28][CH2:29][OH:30].[CH3:31][C:32](=[O:33])[OH:34].[OH-:35].[OH-:37].[Pd+2:36].[c:1]1([CH:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:22]2)[N:8]2[CH2:9][CH:10]([N:12]3[CH2:13][CH2:14][N:15]([C:18]([CH2:19][CH3:20])=[O:21])[CH2:16][CH2:17]3)[CH2:11]2)[cH:23][cH:24][cH:25][cH:26][cH:27]1>>[NH:8]1[CH2:9][CH:10]([N:12]2[CH2:13][CH2:14][N:15]([C:18]([CH2:19][CH3:20])=[O:21])[CH2:16][CH2:17]2)[CH2:11]1

Participants

6

Reactant 5

HCID 176Acetic AcidHCID 702EthanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 16123291HCID 16123291, compound

Product 1

HCID 161232931-Propanone, 1-[4-(3-azetidinyl)-1-piperazinyl]-

Sources & evidence

ORD record
ord-8c6dc0649c6b43d1b280b01d16d58c02
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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