Dichloromethane → 4-[5-(2-Fluoro-ethyl)-imidazol-1-yl]-3,3-dimethyl-isochroman-1-one
Reaction equation
[CH2:22]([N:23]([S:24]([F:25])([F:26])[F:28])[CH2:27][CH3:29])[CH3:30].[Cl:31][CH2:32][Cl:33].[OH:1][CH2:2][CH2:3][c:4]1[cH:5][n:6][cH:7][n:8]1[CH:9]1[C:10]([CH3:20])([CH3:21])[O:11][C:12](=[O:19])[c:13]2[cH:14][cH:15][cH:16][cH:17][c:18]21>>[CH2:2]([CH2:3][c:4]1[cH:5][n:6][cH:7][n:8]1[CH:9]1[C:10]([CH3:20])([CH3:21])[O:11][C:12](=[O:19])[c:13]2[cH:14][cH:15][cH:16][cH:17][c:18]21)[F:28]Participants
4
Sources & evidence
- ORD record
- ord-4153c129063340e8b2f78960e6ffb3e3
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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