10-Bromo-2,7,12-triazatricyclo[6.4.0.02,6]dodeca-1(8),6,9,11-tetraen-5-amine → N-(5-amino-2,7,12-triazatricyclo[6.4.0.02,6]dodeca-1(8),6,9,11-tetraen-10-yl)-5-fluoro-1-[(3-fluorophenyl)methyl]indole-2-carboxamide
Reaction equation
[Br:22][c:23]1[cH:24][c:25]2[c:26]([n:27][cH:28]1)[n:29]1[c:30]([n:31]2)[CH:32]([NH2:35])[CH2:33][CH2:34]1.[F:1][c:2]1[cH:3][c:4]2[cH:5][c:6]([C:19](=[O:20])[NH2:21])[n:7]([CH2:11][c:12]3[cH:13][c:14]([F:18])[cH:15][cH:16][cH:17]3)[c:8]2[cH:9][cH:10]1>>[F:1][c:2]1[cH:3][c:4]2[cH:5][c:6]([C:19](=[O:20])[NH:21][c:23]3[cH:24][c:25]4[c:26]([n:27][cH:28]3)[n:29]3[c:30]([n:31]4)[CH:32]([NH2:35])[CH2:33][CH2:34]3)[n:7]([CH2:11][c:12]3[cH:13][c:14]([F:18])[cH:15][cH:16][cH:17]3)[c:8]2[cH:9][cH:10]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-aece6bd60cd44154ae892167a90d39aa
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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