Methyl iodide → 1-Methyl-3-{6-[4-(2-trifluoromethylbenzoyl)piperazin-1-YL]pyridazin-3-YL}imidazolidin-2-one
Reaction equation
[F:3][C:4]([c:5]1[c:6]([C:7](=[O:8])[N:9]2[CH2:10][CH2:11][N:12]([c:15]3[cH:16][cH:17][c:18]([N:21]4[C:22](=[O:26])[NH:23][CH2:24][CH2:25]4)[n:19][n:20]3)[CH2:13][CH2:14]2)[cH:27][cH:28][cH:29][cH:30]1)([F:31])[F:32].[I:1][CH3:2]>>[CH3:2][N:23]1[C:22](=[O:26])[N:21]([c:18]2[cH:17][cH:16][c:15]([N:12]3[CH2:11][CH2:10][N:9]([C:7]([c:6]4[c:5]([C:4]([F:3])([F:31])[F:32])[cH:30][cH:29][cH:28][cH:27]4)=[O:8])[CH2:14][CH2:13]3)[n:20][n:19]2)[CH2:25][CH2:24]1Participants
3
Sources & evidence
- ORD record
- ord-2856a3cd854347f589e6e9a0e9b7fce8
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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