Octahydroindolizin-7-one → 7-[5-(4-Fluorophenyl)-4-pyridin-4-ylthiophen-3-yl]-1,2,3,5,8,8a-hexahydroindolizine
Reaction equation
[Br:1][c:2]1[c:3](-[c:14]2[cH:15][cH:16][n:17][cH:18][cH:19]2)[c:4](-[c:7]2[cH:8][cH:9][c:10]([F:13])[cH:11][cH:12]2)[s:5][cH:6]1.[Br:20][c:21]1[c:22](-[c:23]2[cH:24][cH:25][n:26][cH:27][cH:28]2)[c:29](-[c:30]2[cH:31][cH:32][c:33]([F:34])[cH:35][cH:36]2)[nH:37][n:38]1.[CH2:39]1[CH2:40][CH2:41][N:42]2[CH2:43][CH2:44][C:45](=[O:48])[CH2:46][CH:47]12>>[c:2]1([C:45]2=[CH:44][CH2:43][N:42]3[CH2:41][CH2:40][CH2:39][CH:47]3[CH2:46]2)[c:3](-[c:14]2[cH:15][cH:16][n:17][cH:18][cH:19]2)[c:4](-[c:7]2[cH:8][cH:9][c:10]([F:13])[cH:11][cH:12]2)[s:5][cH:6]1Participants
4
Sources & evidence
- ORD record
- ord-c2c13944181c495dae991b8d4c598c98
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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