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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 955313Generated: October 30, 2026

Methanol → 4-Chloro-7-fluoro-6-hydroxy-3-quinolinecarbonitrile

https://huagongshe.com/reaction/955313

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantTrifluoroacetic acidHCID 6422—
ReactantThioanisoleHCID 7520—
ReactantEthyl AcetateHCID 8857—
Reactant4-Chloro-7-fluoro-6-(phenylmethoxy)-3-quinolinecarbonitrileHCID 23498116—
Product4-Chloro-7-fluoro-6-hydroxy-3-quinolinecarbonitrileHCID 23498076—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-b8db4d3e02ec4e17a3d65b0fd86e3c65
Source noteValidation data from https://doi.org/10.1039/C8SC04228D