Methanol → [2-(dibenzylamino)-6,7-dihydro-5H-cyclopenta[b]pyridin-7-yl]acetonitrile

HRID 955435Notes

Reaction equation

HRID 955435 reaction equation
[C+4:30].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]([c:9]1[cH:10][cH:11][c:12]2[c:13]([n:14]1)[C:15](=[CH:18][C:19]#[N:20])[CH2:16][CH2:17]2)[CH2:21][c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1.[CH3:28][OH:29].[OH-:31].[OH-:33].[OH-:34].[OH-:35].[OH-:36].[OH-:37].[Pd+2:32]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]([c:9]1[cH:10][cH:11][c:12]2[c:13]([n:14]1)[CH:15]([CH2:18][C:19]#[N:20])[CH2:16][CH2:17]2)[CH2:21][c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1

Participants

6

Reactant 5

HCID 887MethanolHCID 961Hydroxide6×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 68702395[2-(dibenzylamino)-5,6-dihydro-7H-cyclopenta[b]pyridin-7-ylidene]acetonitrileHCID 178420935HCID 178420935, compound

Product 1

HCID 59145908[2-(dibenzylamino)-6,7-dihydro-5H-cyclopenta[b]pyridin-7-yl]acetonitrile

Sources & evidence

ORD record
ord-89fb6d9204c040f49986382e52caf4cb
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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