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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 955474Generated: October 30, 2026

Acetate → Racemic methyl-4-(5-{3-[(5-fluoro-4-methylpyrimidin-2-yl)amino]-5-methylphenyl}-1,3-thiazol-2-yl)-4-hydroxy-2,2-dimethylcyclohexanecarboxylate

https://huagongshe.com/reaction/955474

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetateHCID 175—
ReactantCarbonate IonHCID 19660—
ReactantCesium cationHCID 104967—
ReactantAllyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 105144—
Reactant2-Chloro-5-fluoro-4-methylpyrimidineHCID 20778073—
ReactantMethyl 4-(5-(3-amino-5-methylphenyl)thiazol-2-yl)-4-hydroxy-2,2-dimethylcyclohexanecarboxylateHCID 67429727—
ProductRacemic methyl-4-(5-{3-[(5-fluoro-4-methylpyrimidin-2-yl)amino]-5-methylphenyl}-1,3-thiazol-2-yl)-4-hydroxy-2,2-dimethylcyclohexanecarboxylateHCID 67250082—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-12c4e7e67d69430480d1346467ae6ef9
Source noteValidation data from https://doi.org/10.1039/C8SC04228D