1-Methylhydantoin → 3-(2-{[5-Bromo-2-({3-chloro-4-[(2-methylphenyl)carbonyl]phenyl}amino)benzyl]oxy}ethyl)-1-methylimidazolidine-2,4-dione

HRID 955502Notes

Reaction equation

HRID 955502 reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH2:25][O:26][CH2:27][CH2:28][OH:29])[c:5]([NH:8][c:9]2[cH:10][c:11]([Cl:24])[c:12]([C:15](=[O:16])[c:17]3[c:18]([CH3:23])[cH:19][cH:20][cH:21][cH:22]3)[cH:13][cH:14]2)[cH:6][cH:7]1.[CH3:30][N:31]1[C:32](=[O:33])[NH:34][C:35](=[O:36])[CH2:37]1>>[Br:1][c:2]1[cH:3][c:4]([CH2:25][O:26][CH2:27][CH2:28][N:34]2[C:32](=[O:33])[N:31]([CH3:30])[CH2:37][C:35]2=[O:36])[c:5]([NH:8][c:9]2[cH:10][c:11]([Cl:24])[c:12]([C:15](=[O:16])[c:17]3[c:18]([CH3:23])[cH:19][cH:20][cH:21][cH:22]3)[cH:13][cH:14]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 692171-MethylhydantoinHCID 10227340[4-({4-Bromo-2-[(2-hydroxyethoxy)methyl]phenyl}amino)-2-chlorophenyl](2-methylphenyl)methanone

Product 1

HCID 221745533-(2-{[5-Bromo-2-({3-chloro-4-[(2-methylphenyl)carbonyl]phenyl}amino)benzyl]oxy}ethyl)-1-methylimidazolidine-2,4-dione

Sources & evidence

ORD record
ord-c72f91777f4043ab9b42d224740a014b
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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