Triethyl phosphite → 8-(N-benzyloxycarbonylamino)-4-diethylphosphonomethyl-2-formylamino-oct-3-enoic acid methyl ester
Reaction equation
[CH3:11][O:12][C:13]([CH:14]([CH:15]=[C:16]([CH2:17][CH2:18][CH2:19][CH2:20][NH:21][C:22](=[O:23])[O:24][CH2:25][c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1)[CH2:32][Br:33])[NH:34][CH:35]=[O:36])=[O:37].[P:1]([O:2][CH2:3][CH3:4])([O:5][CH2:6][CH3:7])[O:8][CH2:9][CH3:10]>>[P:1]([O:2][CH2:3][CH3:4])([O:5][CH2:6][CH3:7])(=[O:8])[CH2:32][C:16](=[CH:15][CH:14]([C:13]([O:12][CH3:11])=[O:37])[NH:34][CH:35]=[O:36])[CH2:17][CH2:18][CH2:19][CH2:20][NH:21][C:22](=[O:23])[O:24][CH2:25][c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1Participants
3
Sources & evidence
- ORD record
- ord-0bee2378cd9443d9ad71428cf02cb6b8
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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