Pyrrolidine-1-sulfonic acid [1-(4-oxo-4,5-dihydro-thiazol-2-yl)-piperidine-4-carbonyl]-amide → Pyrrolidine-1-sulfonic acid (1-{5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-4-oxo-4,5-dihydro-thiazol-2-yl}-piperidine-4-carbonyl)-amide
Reaction equation
[Cl:1][c:2]1[cH:3][c:4]([C:20]([F:21])([F:22])[F:23])[c:5]([CH2:6][n:7]2[n:8][cH:9][c:10]3[cH:11][c:12]([CH:16]=[O:17])[cH:13][cH:14][c:15]23)[cH:18][cH:19]1.[O:24]=[C:25]1[N:26]=[C:27]([N:30]2[CH2:31][CH2:32][CH:33]([C:36](=[O:37])[NH:38][S:39](=[O:40])(=[O:41])[N:42]3[CH2:43][CH2:44][CH2:45][CH2:46]3)[CH2:34][CH2:35]2)[S:28][CH2:29]1>>[Cl:1][c:2]1[cH:3][c:4]([C:20]([F:21])([F:22])[F:23])[c:5]([CH2:6][n:7]2[n:8][cH:9][c:10]3[cH:11][c:12]([CH:16]=[C:29]4[C:25](=[O:24])[N:26]=[C:27]([N:30]5[CH2:31][CH2:32][CH:33]([C:36](=[O:37])[NH:38][S:39](=[O:40])(=[O:41])[N:42]6[CH2:43][CH2:44][CH2:45][CH2:46]6)[CH2:34][CH2:35]5)[S:28]4)[cH:13][cH:14][c:15]23)[cH:18][cH:19]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-4452a12280dc4de6bd6519d7b6429f59
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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