2-(Bromomethyl)-1,3-difluorobenzene → Methyl 2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)methyl]benzimidazole-4-carboxylate
Reaction equation
[F:1][c:2]1[c:3](-[c:9]2[nH:10][c:11]3[c:12]([n:13]2)[cH:14][cH:15][cH:16][c:17]3[C:18](=[O:19])[O:20][CH3:21])[c:4]([F:8])[cH:5][cH:6][cH:7]1.[F:22][c:23]1[c:24]([CH2:25][Br:26])[c:27]([F:31])[cH:28][cH:29][cH:30]1>>[F:1][c:2]1[c:3](-[c:9]2[n:10][c:11]3[c:12]([n:13]2[CH2:25][c:24]2[c:23]([F:22])[cH:30][cH:29][cH:28][c:27]2[F:31])[cH:14][cH:15][cH:16][c:17]3[C:18](=[O:19])[O:20][CH3:21])[c:4]([F:8])[cH:5][cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-34d9e078436d403a8de8a225f844ea15
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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