8-(2,6-Difluoro-3,5-dimethoxy-phenyl)quinoxaline-5-carboxylic acid → 8-(2,6-Difluoro-3,5-dimethoxy-phenyl)-quinoxaline-5-carboxylic acid [6-(4-methyl-piperazin-1-ylmethyl)-pyridin-3-yl]-amide
Reaction equation
[CH3:26][N:27]1[CH2:28][CH2:29][N:30]([CH2:33][c:34]2[cH:35][cH:36][c:37]([NH2:40])[cH:38][n:39]2)[CH2:31][CH2:32]1.[F:1][c:2]1[c:3](-[c:13]2[cH:14][cH:15][c:16]([C:23](=[O:24])[OH:25])[c:17]3[n:18][cH:19][cH:20][n:21][c:22]23)[c:4]([F:12])[c:5]([O:10][CH3:11])[cH:6][c:7]1[O:8][CH3:9]>>[F:1][c:2]1[c:3](-[c:13]2[cH:14][cH:15][c:16]([C:23](=[O:25])[NH:40][c:37]3[cH:36][cH:35][c:34]([CH2:33][N:30]4[CH2:29][CH2:28][N:27]([CH3:26])[CH2:32][CH2:31]4)[n:39][cH:38]3)[c:17]3[n:18][cH:19][cH:20][n:21][c:22]23)[c:4]([F:12])[c:5]([O:10][CH3:11])[cH:6][c:7]1[O:8][CH3:9]Participants
3
Sources & evidence
- ORD record
- ord-2b89b621eb0f4c218846d8ff76309344
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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