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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 955952Generated: October 30, 2026

1,2-Dichloroethane → (2,4-Bis-benzyloxy-5-isopropenyl-phenyl)-[5-(4-hydroxy-1-methyl-piperidin-4-yl)-1,3-dihydro-isoindol-2-yl]-methanone

https://huagongshe.com/reaction/955952

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantHydrochloric AcidHCID 313—
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantEthyl AcetateHCID 8857—
ReactantHOAtHCID 181649—
Reactant4-(2,3-Dihydro-1H-isoindol-5-yl)-1-methyl-4-piperidinolHCID 11955867—
Reactant2,4-Bis(benzyloxy)-5-isopropenylbenzoic acidHCID 49864016—
Product(2,4-Bis-benzyloxy-5-isopropenyl-phenyl)-[5-(4-hydroxy-1-methyl-piperidin-4-yl)-1,3-dihydro-isoindol-2-yl]-methanoneHCID 46915491—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-ed7337bdac9644a79cc60701e8edad74
Source noteValidation data from https://doi.org/10.1039/C8SC04228D