Methanol → 5-[Tert-butyl(dimethyl)silyl]oxypiperidin-3-ol
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH:7]1[CH2:8][CH:9]([OH:22])[CH2:10][N:11]([CH2:13][c:14]2[cH:15][cH:16][c:17]([O:18][CH3:19])[cH:20][cH:21]2)[CH2:12]1)([CH3:23])[CH3:24].[CH3:27][OH:28].[H:25][H:26]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH:7]1[CH2:8][CH:9]([OH:22])[CH2:10][NH:11][CH2:12]1)([CH3:23])[CH3:24]Participants
4
Sources & evidence
- ORD record
- ord-8e20305a99414a49a420b353e7382894
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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