7-(Trifluoromethyl)-1,2,3,4-tetrahydroquinoline → (5-methylsulfonyl-2-propan-2-yloxyphenyl)-[7-(trifluoromethyl)-3,4-dihydro-2H-quinolin-1-yl]methanone
Reaction equation
[CH:15]([CH3:16])([CH3:17])[O:18][c:19]1[c:20]([C:21](=[O:22])[OH:23])[cH:24][c:25]([S:28](=[O:29])(=[O:30])[CH3:31])[cH:26][cH:27]1.[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]2[c:11]([cH:12]1)[NH:10][CH2:9][CH2:8][CH2:7]2)([F:13])[F:14]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]2[c:11]([cH:12]1)[N:10]([C:21]([c:20]1[c:19]([O:18][CH:15]([CH3:16])[CH3:17])[cH:27][cH:26][c:25]([S:28](=[O:29])(=[O:30])[CH3:31])[cH:24]1)=[O:22])[CH2:9][CH2:8][CH2:7]2)([F:13])[F:14]Participants
3
Sources & evidence
- ORD record
- ord-317683e99f1d4213aacafbdaf2eb3b2d
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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