Bicarbonate Ion → 2-(Chloromethyl)-6-methoxypyridine

HRID 956233Notes

Reaction equation

[CH3:1][O:2][c:3]1[cH:4][cH:5][cH:6][c:7]([CH2:9][OH:10])[n:8]1.[Cl:20][CH2:21][Cl:22].[Na+:15].[OH:16][C:17](=[O:18])[O-:19].[S:11]([Cl:12])([Cl:13])=[O:14]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][cH:6][c:7]([CH2:9][Cl:13])[n:8]1

Participants

Reactant 5

HCID 769Bicarbonate Ion

HCID 923Sodium ion

HCID 6344Dichloromethane

HCID 24386Thionyl Chloride

HCID 12325389(6-Methoxypyridin-2-yl)methanol

Product 1

HCID 178542282-(Chloromethyl)-6-methoxypyridine

Sources & evidence

ORD record: ord-851c6797e7a34eb09d2c965a9b28e168
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…