2-Methylphenyl boronic acid → 4-(2-Methylphenyl)-6-[3,5-bis(trifluoromethyl)benzyl]-6,7,8,9-tetrahydro-5H-10-oxa-1,6-diazabenzocyclooctene-5-one
Reaction equation
[CH3:30][c:31]1[c:32]([B:37]([OH:38])[OH:39])[cH:33][cH:34][cH:35][cH:36]1.[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][N:7]2[C:8](=[O:20])[c:9]3[c:10]([n:15][cH:16][cH:17][c:18]3[I:19])[O:11][CH2:12][CH2:13][CH2:14]2)[cH:21][c:22]([C:24]([F:25])([F:26])[F:27])[cH:23]1)([F:28])[F:29]>>[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][N:7]2[C:8](=[O:20])[c:9]3[c:10]([n:15][cH:16][cH:17][c:18]3-[c:32]3[c:31]([CH3:30])[cH:36][cH:35][cH:34][cH:33]3)[O:11][CH2:12][CH2:13][CH2:14]2)[cH:21][c:22]([C:24]([F:25])([F:26])[F:27])[cH:23]1)([F:28])[F:29]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-1a2c00ae779646f6a96048e2b2de2024
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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