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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 956392Generated: October 26, 2026

Dimethylformamide → 5-[3-(tert-Butyl-dimethyl-silanyloxy)-benzylcarbamoyl]-3-phenyl-thiophene-2-carboxylic acid methyl ester

https://huagongshe.com/reaction/956392

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
ReactantHexafluorophosphateHCID 9886—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantO-benzotriazol-1-yl-tetramethyluroniumHCID 130500—
Reactant3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]benzenemethanamineHCID 22266169—
Reactant5-(Methoxycarbonyl)-4-phenylthiophene-2-carboxylic acidHCID 58121085—
Product5-[3-(tert-Butyl-dimethyl-silanyloxy)-benzylcarbamoyl]-3-phenyl-thiophene-2-carboxylic acid methyl esterHCID 68226964—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-67a5a374f2734040b8607e990f1b2667
Source noteValidation data from https://doi.org/10.1039/C8SC04228D