3-Fluoro-4-methylaniline → Methyl 4-[(3-fluoro-4-methylphenyl)amino]-5-methylthiothiophene-2-carboxylate
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:8](=[S:9])[O:10][CH3:11])[s:5][c:6]1[CH3:7].[C:12](=[O:13])([O-:14])[O-:15].[Cs+:16].[Cs+:17].[F:18][c:19]1[cH:20][c:21]([NH2:22])[cH:23][cH:24][c:25]1[CH3:26]>>[c:2]1([NH:22][c:21]2[cH:20][c:19]([F:18])[c:25]([CH3:26])[cH:24][cH:23]2)[cH:3][c:4]([C:8](=[S:9])[O:10][CH3:11])[s:5][c:6]1[CH3:7]Participants
5
Sources & evidence
- ORD record
- ord-552d5904f5984fe79d7b5ac2cbea76b3
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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