Pyridine → Fluoride Ion

HRID 956530Notes

Reaction equation

HRID 956530 reaction equation
[Cl:29][CH2:30][Cl:31].[F:7][N:8]1[N:9]=[C:10]([F:11])[CH:12]=[C:13]([F:14])[NH:15]1.[NH2:16][CH2:17][CH2:18][c:19]1[c:20]([C:21](=[O:22])[OH:23])[cH:24][cH:25][c:26]([Cl:28])[n:27]1.[cH:1]1[cH:2][cH:3][n:4][cH:5][cH:6]1>>[F-:7].[NH2:16][CH2:17][CH2:18][c:19]1[c:20]([C:21](=[O:22])[OH:23])[cH:24][cH:25][c:26]([Cl:28])[n:27]1

Participants

6

Reactant 4

HCID 1049PyridineHCID 6344DichloromethaneHCID 216944332,4,6-Trifluoro-1,2,3-triazineHCID 866423332-(Aminoethyl)-6-chloronicotinic acid

Product 2

HCID 28179Fluoride IonHCID 866423332-(Aminoethyl)-6-chloronicotinic acid

Sources & evidence

ORD record
ord-32dac2da56d54f56aadcb726395af17a
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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