3-(Bromomethyl)-1H-indazole, N1-BOC protected → 3-(6-[(benzyl-isopropyl-carbamoyl)-methyl]-5-oxo-1-phenyl-5,6-dihydro-4H-2,3,6,10b-tetraaza-benzo[e]azulen-4-ylmethyl}-indazole-1-carboxylic acid tert-butyl ester
Reaction equation
[C:36]([CH3:37])([CH3:38])([CH3:39])[O:40][C:41](=[O:42])[n:43]1[n:44][c:45]([CH2:52][Br:53])[c:46]2[cH:47][cH:48][cH:49][cH:50][c:51]12.[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]([C:9]([CH2:10][N:11]1[c:12]2[c:13]([cH:28][cH:29][cH:30][cH:31]2)-[n:14]2[c:15](-[c:22]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)[n:16][n:17][c:18]2[CH2:19][C:20]1=[O:21])=[O:32])[CH:33]([CH3:34])[CH3:35]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]([C:9]([CH2:10][N:11]1[c:12]2[c:13]([cH:28][cH:29][cH:30][cH:31]2)-[n:14]2[c:15](-[c:22]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)[n:16][n:17][c:18]2[CH:19]([CH2:52][c:45]2[n:44][n:43]([C:41]([O:40][C:36]([CH3:37])([CH3:38])[CH3:39])=[O:42])[c:51]3[c:46]2[cH:47][cH:48][cH:49][cH:50]3)[C:20]1=[O:21])=[O:32])[CH:33]([CH3:34])[CH3:35]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-acefe94cec524be09b570c73b8b442cf
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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