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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 956592Generated: October 29, 2026

Hydrochloric Acid → 1'-{[3,5-Diethoxy-4-(1H-pyrazol-4-yl)phenyl]carbonyl}-6-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)spiro[chroman-2,4'-piperidin]-4-one

https://huagongshe.com/reaction/956592

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
Reactant1-HydroxybenzotriazoleHCID 75771—
Reactant3,5-diethoxy-4-(1H-pyrazol-4-yl)benzoic acidHCID 66781996—
Reactant3-[4-Oxospiro(chroman-2,4'-piperidin)-6-yl]-5-oxo-1,2,4-oxadiazoleHCID 136058073—
Product1'-{[3,5-Diethoxy-4-(1H-pyrazol-4-yl)phenyl]carbonyl}-6-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)spiro[chroman-2,4'-piperidin]-4-oneHCID 135910172—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-3f42845c8b1a4caa98275b6580d0c317
Source noteValidation data from https://doi.org/10.1039/C8SC04228D