2-Acetamidopyridine-5-boronic acid pinacol ester → N-(5-(6-acetamidopyridin-3-yl)thiazolo[5,4-b]pyridin-2-yl)-4-(1-hydroxy-2-methylpropan-2-yl)benzamide
Reaction equation
[Br:20][c:21]1[cH:22][cH:23][c:24]2[c:25]([n:26]1)[s:27][c:28]([NH:30][C:31]([c:32]1[cH:33][cH:34][c:35]([C:38]([CH2:39][OH:40])([CH3:41])[CH3:42])[cH:36][cH:37]1)=[O:43])[n:29]2.[CH3:1][C:2]1([CH3:3])[C:4]([CH3:5])([CH3:6])[O:7][B:8]([c:9]2[cH:10][cH:11][c:12]([NH:15][C:16]([CH3:17])=[O:18])[n:13][cH:14]2)[O:19]1>>[c:9]1(-[c:21]2[cH:22][cH:23][c:24]3[c:25]([n:26]2)[s:27][c:28]([NH:30][C:31]([c:32]2[cH:33][cH:34][c:35]([C:38]([CH2:39][OH:40])([CH3:41])[CH3:42])[cH:36][cH:37]2)=[O:43])[n:29]3)[cH:10][cH:11][c:12]([NH:15][C:16]([CH3:17])=[O:18])[n:13][cH:14]1Participants
3
Sources & evidence
- ORD record
- ord-8c6c3c5d2d804945aea51e8e71acd2ca
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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