5-(Chloromethyl)-2-(trifluoromethyl)pyridine → 6-(2-chlorophenyl)-7-(4-chlorophenyl)-2-((6-(trifluoromethyl)pyridin-3-yl)methyl)-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one
Reaction equation
[Cl:1][c:2]1[c:3](-[c:8]2[c:9](-[c:18]3[cH:19][cH:20][c:21]([Cl:24])[cH:22][cH:23]3)[cH:10][c:11]3[n:12]([n:13]2)[c:14](=[O:17])[nH:15][n:16]3)[cH:4][cH:5][cH:6][cH:7]1.[Cl:25][CH2:26][c:27]1[cH:28][cH:29][c:30]([C:33]([F:34])([F:35])[F:36])[n:31][cH:32]1.[F:37][C:38]([F:39])([F:40])[c:41]1[cH:42][cH:43][c:44]([CH2:45][n:46]2[c:47](=[O:48])[n:49]3[n:50][c:51](-[c:52]4[cH:53][cH:54][cH:55][cH:56][c:57]4[Cl:58])[c:59](-[c:60]4[cH:61][cH:62][c:63]([Cl:64])[cH:65][cH:66]4)[cH:67][c:68]3[n:69]2)[cH:70][cH:71]1>>[Cl:1][c:2]1[c:3](-[c:8]2[c:9](-[c:18]3[cH:19][cH:20][c:21]([Cl:24])[cH:22][cH:23]3)[cH:10][c:11]3[n:12]([n:13]2)[c:14](=[O:17])[n:15]([CH2:26][c:27]2[cH:28][cH:29][c:30]([C:33]([F:34])([F:35])[F:36])[n:31][cH:32]2)[n:16]3)[cH:4][cH:5][cH:6][cH:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-2c8a69e9b8af43b1b749ba7b1879781e
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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