5-bromo-N-(1,3-dihydroxy-2-methylpropan-2-yl)pyridine-3-sulfonamide → 5-[7-Trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-pyridine-3-sulfonic acid (2-hydroxy-1-hydroxymethyl-1-methyl-ethyl)-amide
Reaction equation
[C:1](#[CH:2])[c:3]1[cH:4][n:5][n:6]2[c:7]1[n:8][c:9](-[c:16]1[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]1)[cH:10][c:11]2[C:12]([F:13])([F:14])[F:15].[OH:26][CH2:27][C:28]([CH3:29])([CH2:30][OH:31])[NH:32][S:33](=[O:34])(=[O:35])[c:36]1[cH:37][n:38][cH:39][c:40]([Br:42])[cH:41]1>>[C:1](#[C:2][c:40]1[cH:39][n:38][cH:37][c:36]([S:33]([NH:32][C:28]([CH2:27][OH:26])([CH3:29])[CH2:30][OH:31])(=[O:34])=[O:35])[cH:41]1)[c:3]1[cH:4][n:5][n:6]2[c:7]1[n:8][c:9](-[c:16]1[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]1)[cH:10][c:11]2[C:12]([F:13])([F:14])[F:15]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-f8d244cbdeec49ef992428047ab89f44
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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