[6-Bromo-5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-(1,1-Dioxo-1lambda6-thiomorpholin-4-yl)-methanone → [6-Bromo-1-isopropyl-5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-(1,1-dioxo-1lambda6-thiomorpholin-4-yl)-methanone

HRID 956722Notes

Reaction equation

HRID 956722 reaction equation
[Br:1][c:2]1[c:3]([O:21][CH:22]2[CH2:23][CH2:24][N:25]([CH:28]([CH3:29])[CH3:30])[CH2:26][CH2:27]2)[cH:4][c:5]2[cH:6][c:7]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][S:16](=[O:19])(=[O:20])[CH2:17][CH2:18]3)[nH:8][c:9]2[cH:10]1.[CH:31]([CH3:32])([CH3:33])[CH2:34][S:35]([O-:36])(=[O:37])=[O:38]>>[Br:1][c:2]1[c:3]([O:21][CH:22]2[CH2:23][CH2:24][N:25]([CH:28]([CH3:29])[CH3:30])[CH2:26][CH2:27]2)[cH:4][c:5]2[cH:6][c:7]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][S:16](=[O:19])(=[O:20])[CH2:17][CH2:18]3)[n:8]([CH:31]([CH3:32])[CH3:33])[c:9]2[cH:10]1

Participants

3

Reactant 2

HCID 16739609[6-Bromo-5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-(1,1-Dioxo-1lambda6-thiomorpholin-4-yl)-methanoneHCID 22141912Isopropyl-methanesulfonate

Product 1

HCID 16739675[6-Bromo-1-isopropyl-5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-(1,1-dioxo-1lambda6-thiomorpholin-4-yl)-methanone

Sources & evidence

ORD record
ord-44b0a14343ac4fa4ae9f9058adb0bbc5
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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