N-[2-(4-bromophenoxy)cyclopentyl]propane-2-sulfonamide → N-[2-(4-bromo-3-fluorophenoxy)cyclopentyl]propane-2-sulfonamide
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([O:6][CH:7]2[CH:8]([NH:12][S:13](=[O:14])(=[O:15])[CH:16]([CH3:17])[CH3:18])[CH2:9][CH2:10][CH2:11]2)[cH:19][cH:20]1.[Br:21][c:22]1[cH:23][cH:24][c:25]([O:26][CH:27]2[CH2:28][CH2:29][CH2:30][CH:31]2[NH2:32])[cH:33][c:34]1[F:35]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([O:6][CH:7]2[CH:8]([NH:12][S:13](=[O:14])(=[O:15])[CH:16]([CH3:17])[CH3:18])[CH2:9][CH2:10][CH2:11]2)[cH:19][c:20]1[F:35]Participants
3
Sources & evidence
- ORD record
- ord-22717e908de04fdd96a11bbb8ca927bd
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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