Ethanol → 6-Amino-4-[(4-bromophenyl)amino]-3-quinolinecarbonitrile

HRID 956903Notes

Reaction equation

HRID 956903 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([NH:8][c:9]2[c:10]([C:22]#[N:23])[cH:11][n:12][c:13]3[cH:14][cH:15][c:16]([N+:19]([O-:20])=[O:21])[cH:17][c:18]23)[cH:6][cH:7]1.[CH3:27][CH2:28][OH:29].[Sn:24]([Cl:25])[Cl:26]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([NH:8][c:9]2[c:10]([C:22]#[N:23])[cH:11][n:12][c:13]3[cH:14][cH:15][c:16]([NH2:19])[cH:17][c:18]23)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 702EthanolHCID 24479Stannous ChlorideHCID 224667624-[(4-Bromophenyl)amino]-6-nitro-3-quinolinecarbonitrile

Product 1

HCID 224665976-Amino-4-[(4-bromophenyl)amino]-3-quinolinecarbonitrile

Sources & evidence

ORD record
ord-5c4b1a6e6b6f40a6b9e3ace94bca1173
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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