Dichloromethane → N-(1-{4-[2-(3,4-dichlorophenyl)-[1,3]dioxolan-2-yl]piperidin-1-yl-methyl}-2-methylpropyl)-4-methylbenzamide
Reaction equation
[CH2:36]([Cl:37])[Cl:38].[Cl:1][c:2]1[cH:3][c:4]([C:9]2([CH:14]3[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]3)[O:10][CH2:11][CH2:12][O:13]2)[cH:5][cH:6][c:7]1[Cl:8].[c:20]1([CH3:35])[cH:21][cH:22][c:23]([C:26](=[O:27])[NH:28][CH:29]([CH:30]([CH3:31])[CH3:32])[CH:33]=[O:34])[cH:24][cH:25]1>>[Cl:1][c:2]1[cH:3][c:4]([C:9]2([CH:14]3[CH2:15][CH2:16][N:17]([CH2:33][CH:29]([NH:28][C:26]([c:23]4[cH:22][cH:21][c:20]([CH3:35])[cH:25][cH:24]4)=[O:27])[CH:30]([CH3:31])[CH3:32])[CH2:18][CH2:19]3)[O:10][CH2:11][CH2:12][O:13]2)[cH:5][cH:6][c:7]1[Cl:8]Participants
4
Sources & evidence
- ORD record
- ord-3f36e9b1d92f400086ee660b839e7ec2
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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