5-Bromo-2-thiophenesulfonamide → 5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]-oxazin-6-yl)-thiophene-2-sulfonamide

HRID 957268Notes

Reaction equation

HRID 957268 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([S:7](=[O:8])(=[O:9])[NH2:10])[s:6]1.[CH3:11][C:12]1([CH3:26])[O:13][C:14](=[O:25])[NH:15][c:16]2[c:17]1[cH:18][c:19]([B:22]([OH:23])[OH:24])[cH:20][cH:21]2>>[c:2]1(-[c:19]2[cH:18][c:17]3[c:16]([cH:21][cH:20]2)[NH:15][C:14](=[O:25])[O:13][C:12]3([CH3:11])[CH3:26])[cH:3][cH:4][c:5]([S:7](=[O:8])(=[O:9])[NH2:10])[s:6]1

Participants

3

Reactant 2

HCID 12413045-Bromo-2-thiophenesulfonamideHCID 10987806(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-3,1-benzoxazin-6-yl)boronic acid

Product 1

HCID 227366265-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]-oxazin-6-yl)-thiophene-2-sulfonamide

Sources & evidence

ORD record
ord-7903dfab06d049b997fbeedc534d95b8
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…