Boron tribromide → 2-Ethyl-6-[2-(3-hydroxy-pyrrol idine-1-carbonyl)-thieno[3,2-b]pyridin-7-yloxy]-benzofuran-3-carboxylic acid methylamide
Reaction equation
[B:35]([Br:36])([Br:37])[Br:38].[CH3:1][NH:2][C:3](=[O:4])[c:5]1[c:6]([CH2:33][CH3:34])[o:7][c:8]2[c:9]1[cH:10][cH:11][c:12]([O:14][c:15]1[c:16]3[c:17]([n:18][cH:19][cH:20]1)[cH:21][c:22]([C:24](=[O:25])[N:26]1[CH2:27][CH:28]([O:31][CH3:32])[CH2:29][CH2:30]1)[s:23]3)[cH:13]2.[CH3:39][NH:40][C:41]([c:42]1[c:43]2[cH:44][cH:45][c:46]([OH:47])[cH:48][c:49]2[s:50][c:51]1[CH3:52])=[O:53]>>[CH3:1][NH:2][C:3](=[O:4])[c:5]1[c:6]([CH2:33][CH3:34])[o:7][c:8]2[c:9]1[cH:10][cH:11][c:12]([O:14][c:15]1[c:16]3[c:17]([n:18][cH:19][cH:20]1)[cH:21][c:22]([C:24](=[O:25])[N:26]1[CH2:27][CH:28]([OH:31])[CH2:29][CH2:30]1)[s:23]3)[cH:13]2Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-8597245331e94ba4af3b7897079f90a5
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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