Carbon Tetrachloride → Ethyl 5-bromo-6-hydroxy-2-(trifluoromethyl)nicotinate

HRID 957338Notes

Reaction equation

HRID 957338 reaction equation
[Br:17][N:18]1[C:19](=[O:20])[CH2:21][CH2:22][C:23]1=[O:24].[C:25]([Cl:26])([Cl:27])([Cl:28])[Cl:29].[O:1]=[c:2]1[cH:3][cH:4][c:5]([C:12](=[O:13])[O:14][CH2:15][CH3:16])[c:6]([C:8]([F:9])([F:10])[F:11])[nH:7]1>>[O:1]=[c:2]1[c:3]([Br:17])[cH:4][c:5]([C:12](=[O:13])[O:14][CH2:15][CH3:16])[c:6]([C:8]([F:9])([F:10])[F:11])[nH:7]1

Participants

4

Reactant 3

HCID 5943Carbon TetrachlorideHCID 67184N-bromobutanimideHCID 18374262Ethyl 6-oxo-2-(trifluoromethyl)-1,6-dihydropyridine-3-carboxylate

Product 1

HCID 57900861Ethyl 5-bromo-6-hydroxy-2-(trifluoromethyl)nicotinate

Sources & evidence

ORD record
ord-022ced99078145569bb1bdf509c6c0a2
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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