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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 957353Generated: November 2, 2026

1,2-Dichloroethane → 5-chloro-2-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene)valeric acid (1-(2,6-difluorophenyl)ethyl)amide

https://huagongshe.com/reaction/957353

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
ReactantTrifluoroacetic acidHCID 6422—
ReactantEthyl AcetateHCID 8857—
Reactant1-HydroxybenzotriazoleHCID 75771—
Reactant1-(2,6-Difluorophenyl)ethanamineHCID 16768371—
Reactant5-Chloro-2-[[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]methylidene]pentanoic acidHCID 66839644—
Product5-chloro-2-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene)valeric acid (1-(2,6-difluorophenyl)ethyl)amideHCID 66961009—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-bc52422cdcc3414bb18c471506ed42ce
Source noteValidation data from https://doi.org/10.1039/C8SC04228D