Acetic Acid → tert-Butyl 2-(4-chlorophenyl)piperazine-1-carboxylate

HRID 957361Notes

Reaction equation

HRID 957361 reaction equation
[BH4-:26].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([c:15]2[cH:16][cH:17][c:18]([Cl:21])[cH:19][cH:20]2)[C:10](=[O:14])[NH:11][CH2:12][CH2:13]1.[CH2:28]1[O:29][CH2:30][CH2:31][O:32][CH2:33]1.[CH3:22][C:23](=[O:24])[OH:25].[Na+:27]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([c:15]2[cH:16][cH:17][c:18]([Cl:21])[cH:19][cH:20]2)[CH2:10][NH:11][CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 176Acetic AcidHCID 923Sodium ionHCID 28123BorohydrideHCID 312751,4-DioxaneHCID 67117397HCID 67117397, compound

Product 1

HCID 44558599tert-Butyl 2-(4-chlorophenyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-13c0c9288d4e4ce481758eb7370e2781
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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