Acetic Acid → tert-Butyl 4-(2-(4-aminonaphthalen-1-yloxy)-2-methylpropyl)pyridin-2-ylcarbamate

HRID 957435Notes

Reaction equation

HRID 957435 reaction equation
[C:37]([OH:38])(=[O:39])[CH3:40].[CH3:1][C:2]([CH2:3][c:4]1[cH:5][c:6]([NH:10][C:11]([O:12][C:13]([CH3:14])([CH3:15])[CH3:16])=[O:17])[n:7][cH:8][cH:9]1)([CH3:18])[O:19][c:20]1[cH:21][cH:22][c:23]([N+:30]([O-:31])=[O:32])[c:24]2[cH:25][cH:26][cH:27][cH:28][c:29]12.[CH3:35][OH:36].[H:33][H:34]>>[CH3:1][C:2]([CH2:3][c:4]1[cH:5][c:6]([NH:10][C:11]([O:12][C:13]([CH3:14])([CH3:15])[CH3:16])=[O:17])[n:7][cH:8][cH:9]1)([CH3:18])[O:19][c:20]1[cH:21][cH:22][c:23]([NH2:30])[c:24]2[cH:25][cH:26][cH:27][cH:28][c:29]12

Participants

5

Reactant 4

HCID 176Acetic AcidHCID 887MethanolHCID 67395048tert-Butyl 4-(2-methyl-2-(4-nitronaphthalen-1-yloxy)propyl)pyridin-2-ylcarbamateHCID 178418361HCID 178418361, compound

Product 1

HCID 67359542tert-Butyl 4-(2-(4-aminonaphthalen-1-yloxy)-2-methylpropyl)pyridin-2-ylcarbamate

Sources & evidence

ORD record
ord-5587813e312544d98db8ac4f5766be66
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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